Lucence TripleRISK™
| Test Name | Lucence TripleRISK™ |
| Purpose | To assess risk of developing heart attack, stroke and leukaemia. |
| Test Type | Blood Test |
| Price | $2,616 NETT |
| Appointment Options |
Same-day appointment (subject to availability). Book via WhatsApp: 8893 3757 or email: hello@healthscreening.sg |
| Clinic Locations |
Orchard: 1 Orchard
Blvd #05-09 Camden Medical Centre, S248649 Tanjong Pagar: 72 Anson Rd #01-02 Anson House, S079911 |
What Is the Lucence TripleRISK Test?
The Lucence TripleRISK test is a blood test that detects genetic mutations linked to
higher risks of heart attack, stroke and leukaemia.
It works by detecting clonal haematopoiesis (CH), a type of age-related or lifestyle-related
genetic change in blood cells, even if you currently feel well or healthy. Identifying these
mutations early allows you to take preventive steps and manage your long-term health more
effectively.
At healthscreening.sg, we offer the Lucence TripleRISK blood test at $2,616 NETT,
inclusive of GST.
How Does the TripleRISK Test Work?
The TripleRISK test analyses your blood for clonal haematopoiesis mutations in 11 genes
commonly associated with ageing and long-term lifestyle factors such as
smoking, poor diet and ongoing stress. The genes screened are:
ASXL1, DNMT3A, JAK2, PPM1D, FLT3, IDH2, RUNX1, SF3B1, TET2, TP53, SRSF2.
By measuring the presence and proportion of these mutations, the test calculates your personalised risk
score for developing:
- Heart attack – Up to 12 times higher risk of early myocardial infarction
- Stroke – Approximately 3.1 times higher risk compared to those without CH
- Leukaemia – Around 12.9 times higher likelihood due to CH being a recognised precursor
Who Should Consider the TripleRISK Test?
The TripleRISK test is suitable for adults between 40 and 79 years old who may have personal or family risk factors for cardiovascular or blood-related conditions. You may wish to consider this test if you:
- Have cardiovascular risks such as high blood pressure, diabetes, raised cholesterol levels or a smoking history
- Have experienced a previous heart attack or stroke
- Have close relatives with leukaemia, myelodysplastic syndromes (MDS), or sudden cardiovascular events
- Have undergone chemotherapy or radiation therapy in the past
This test is not recommended if you have recently received a blood transfusion (within the past two weeks) or have had an allogeneic bone marrow transplant. Speak with a doctor first to confirm if the test is suitable for your situation.
What Happens After You Receive the Results?
The TripleRISK test does not provide a diagnosis but offers valuable insight into your future health risks, guiding next steps in prevention and monitoring. Based on your results, your doctor may suggest:
- More frequent health checks and follow-up tests such as ECG, echocardiogram or full blood count
- Lifestyle adjustments including stopping smoking, maintaining a healthy weight, adopting a balanced diet and engaging in regular exercise
- Medical management of existing conditions such as hypertension or diabetes
How Much Does the Lucence TripleRisk Test Cost?
At healthscreening.sg, we provide the TripleRISK test along with other related screenings. The pricing is as follows:
| Test | Price* |
|---|---|
| Consultation | From $49.05 |
| Lucence TripleRISK Blood Test | $2,616 |
| LucenceINSIGHT™ Liquid Biopsy Cancer Screening (From 5 Cancers) | From $1,098 |
| [Optional] Premium Mobile Blood Drawing at Your Home | Additional $54.50 (per location up to 5 pax) |
| Heart Check-Up / Stroke Screening | |
| Apolipoprotein B | $32.70 |
| HsCRP | $38.15 |
| Lipoprotein (a) | $59.95 |
| Fasting Insulin | $66.49 |
| Homocysteine | $74.12 |
|
Essential Lipid Profile: Full Cholesterol Test (Total, LDL, HDL, Triglycerides, HDL Ratio) |
$21.80 |
|
Cardiac Screening 3: Essential Lipid Profile + Apolipoprotein B (ApoB) + HsCRP |
$63.22 |
|
Cardiac Screening 4: Cardiac Screening 3 + Homocysteine + Fasting Insulin + Glucose Note: Fasting is required for accurate results of Fasting Insulin and Glucose. |
$172.22 |
| Electrocardiogram (ECG) | $49.05 |
| 2D Echocardiogram** | $436 |
| CT Coronary Angiogram | From $1329.80 |
| CT Calcium Score Test | $381.50 |
| Carotid Intima-Media Thickness (CIMT) Test | $163.50 |
| Brain CT Scan | From $577.70 |
| Brain MRI Scan | From $1068.20 |
*Prices are NETT and inclusive of GST.
**2D Echocardiogram will be done at the cardiologist clinic and reviewed by the cardiologist
How Long Does the TripleRISK Test Take?
The TripleRISK test involves a routine blood draw at our clinic, which generally takes about 30 to 60 minutes during non-peak hours. Test results are typically ready within 12 working days, after which your doctor will reach out by phone or email to review and explain your results in detail.
How to Prepare for the TripleRISK Test?
Before taking the TripleRISK blood test, it is important to:
- Avoid consuming heavy meals for at least 4 hours before your scheduled appointment
- The test may not be suitable if you have received a blood transfusion in the past 2 weeks or undergone an allogeneic bone marrow transplant
Always follow the specific preparation instructions given by your doctor or our clinic staff prior to your test.
Longevity Health Screening Packages
- Identify potential age-related health risks early through advanced tests designed for lasting wellness.
- Enjoy reassurance with a thorough review by doctors who prioritise preventive healthcare.
- Act now to preserve your vitality, wellbeing, and quality of life for the years ahead.
WhatsApp Us to Book
How to Book an Appointment for the Lucence TripleRISK Test?
Email Us
Why Choose Us?
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Health Screening Singapore
(Anson House)
Health Screening Singapore
(Camden Medical Centre)
Frequently Asked Questions (FAQ)
At healthscreening.sg, we also provide the LucenceINSIGHT liquid biopsy test, which screens for up to 50 different types of cancer beyond the TripleRISK test. These range from focused panels covering five cancers to more comprehensive multi-cancer options. The most suitable test depends on your individual health background, risk profile and screening objectives. Contact us for more information or to book a consultation.
The TripleRISK test evaluates your future risk of heart attack, stroke and leukaemia by identifying clonal haematopoiesis mutations in the blood. These mutations are more common with age and may reveal hidden risks not detected by standard health checks. The test is particularly relevant for people aged 40 to 79 and for those with a personal or family history of cardiovascular or blood-related illnesses.
The TripleRISK test is not MediSave-claimable and is usually not included under standard health insurance coverage in Singapore. However, depending on your insurer, policy type or corporate healthcare plan, some reimbursement may be possible. It is best to confirm directly with your insurance provider.
Yes, at healthscreening.sg, the TripleRISK test can be performed alongside other health screening packages, including cardiovascular, cancer-related or general health assessments. It may also be combined with additional tests such as blood work, imaging scans or ECGs for a more complete evaluation. Consult with our doctors, who can advise on which additional tests are most relevant for you.
Fasting is not required for the TripleRISK blood test, but it is recommended to avoid heavy meals for at least 4 hours before your appointment to help maintain sample quality. If you are scheduled for other fasting blood tests on the same day, your doctor may advise fasting to cover all tests together. Always follow the preparation instructions given by our clinic and check with us if you are uncertain.
The TripleRISK test is a genetic blood test that detects clonal haematopoiesis mutations linked to heart attack, stroke and leukaemia. In contrast, routine blood tests and cholesterol checks focus on general markers such as blood counts, sugar levels or cholesterol. TripleRISK reveals genetic changes that standard tests do not capture, providing additional insight into long-term health risks.
Yes, the TripleRISK test may still be relevant even if you have no symptoms or family history, as clonal mutations can appear gradually with age without any warning signs. The test is designed for proactive risk assessment rather than diagnosis. If you are unsure, consult our doctors who can advise whether it is beneficial based on your personal health profile.
If your TripleRISK results show elevated risk, your doctor may suggest repeating the test either yearly or once every few years, depending on your risk category and overall health context. Repeating the test helps track changes in mutation levels over time and guides ongoing health planning.
The test is generally recommended for adults aged 40 to 79, as clonal haematopoiesis becomes increasingly common with age. While it is possible to carry out the test earlier, its clinical usefulness in younger adults is often limited. If you are unsure, consult our doctors to help determine if early testing is appropriate for you.
A high-risk score indicates a significantly increased likelihood of developing cardiovascular disease or leukaemia in the future due to the presence of clonal mutations. This does not mean disease is certain, but it highlights the importance of closer follow-up, lifestyle adjustments and additional screening. Based on your test results, your doctor will provide a tailored plan according to your overall health status.
Yes, at healthscreening.sg, we offer a mobile blood draw service for the TripleRISK test for patients who prefer home-based collection. This service is available at an additional fee of $54.50 per location and can accommodate groups of up to five people. Please contact our clinic to check availability and arrange a home appointment.