About Dr. Natalia Sutiman

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About Dr. Natalia Sutiman

Dr. Natalia Sutiman, one of our Doctors at ATA Medical.

Dr. Natalia Sutiman

Medical Doctor

MD (Duke-NUS)

Special interests:
Preventive Medicine

Dr Natalia Sutiman is a medical doctor committed to delivering evidence-based and patient-focused care. She holds a Doctor of Medicine (MD) from Duke-NUS Medical School and is currently pursuing her Graduate Diploma in Family Medicine (GDFM).

Her clinical training spans rotations in Internal Medicine, Emergency Medicine and Orthopaedic Surgery at Singapore General Hospital, Paediatric Medicine and Children's Emergency at KK Women's and Children's Hospital, and primary care at SingHealth Polyclinics. This diverse foundation enables her to manage patients of all ages across a broad spectrum of acute and chronic conditions.

Prior to entering medicine, Dr Natalia worked as a pharmacist at Tan Tock Seng Hospital and subsequently in Clinical Pharmacology with SingHealth. During this period, she was involved in clinical trials, therapeutic drug monitoring and genomics research. These experiences continue to inform her careful, science-grounded approach to diagnosis and patient care.

Dr Natalia is also a published researcher with over 400 citations in peer-reviewed journals. Her work centres on pharmacogenomics, which explores how genetic differences influence individual responses to medications. Her research has investigated how genetic variants affect drug metabolism and treatment outcomes in Asian patient populations across conditions including cancer and inflammatory diseases.

While her career spans extensive research and academic work, Dr Natalia has always been drawn to the human dimension of medicine. She places great value on building genuine relationships with her patients, listening attentively to their concerns, and guiding them through medical decisions with clarity and compassion.

She has a particular interest in preventive medicine and longevity, and enjoys working together with patients to make well-informed choices that support their long-term health. She also finds fulfilment in evaluating evolving or complex symptoms and helping patients navigate diagnostic uncertainty in primary care.

Outside of medicine, Dr Natalia enjoys hiking and has a personal appreciation for the health considerations involved in travel and high-altitude adventures. She also enjoys running, yoga, meditation and mindfulness practices, and spending quality time with her loved ones.

Publications

  1. Identifying the thresholds of C-reactive protein, procalcitonin, and interleukin-6 among children ≤ 36 months' old with fever without source at risk of serious bacterial infections: A systematic review and meta-analysis
    2026 · Frontiers in Pediatrics
    Sutiman, N., Lin, J., Sultana, R., Yao, S. H. W., Goh, S. S. M., Rocknathan, S.-K., Ganapathy, S., & Chong, S.-L. (2026). Frontiers in Pediatrics, 14, 1697210. doi.org/10.3389/fped.2026.1697210
  2. Asthma exacerbation in children—Is there pneumonia?
    2025 · Acta Paediatrica
    Kotturu, V., Ganapathy, S., & Sutiman, N. (2025). Acta Paediatrica, 114, 563.
  3. Protocol for the diagnostic performance of C reactive protein, procalcitonin and interleukin-6 for serious bacterial infections among children ≤ 36 months old presenting with fever without source: A systematic review and meta-analysis
    2024 · BMJ Paediatrics Open
    Sutiman, N., Yao, S. H. W., Goh, S. S. M., Sultana, R., & Chong, S.-L. (2024). BMJ Paediatrics Open, 8(1), e002237. doi.org/10.1136/bmjpo-2023-002237
  1. Delayed presentation is associated with serious bacterial infections among febrile infants: A prospective cohort study
    2024 · Annals of the Academy of Medicine, Singapore
    Rajoo, K. P., Sutiman, N., Shih, S., Khoo, Z. X., Ong, G. Y.-K., Wong, L., Piragasam, R., Ganapathy, S., & Chong, S.-L. (2024). Annals of the Academy of Medicine, Singapore, 53(5), 286–292. doi.org/10.47102/annals-acadmedsg.2023350
  2. Cross-ancestry genome-wide association study defines the extended CYP2D6 locus as the principal genetic determinant of endoxifen plasma concentrations
    2023 · Clinical Pharmacology & Therapeutics
    Khor, C. C., Winter, S., Sutiman, N., Mürdter, T. E., Chen, S., Lim, J. S. L., et al. (2023). Clinical Pharmacology & Therapeutics, 113(3), 712–723. doi.org/10.1002/cpt.2846
  3. Cooperative regulation of coupled oncoprotein synthesis and stability in triple-negative breast cancer by EGFR and CDK12/13
    2023 · Proceedings of the National Academy of Sciences
    Ang, H. X., Sutiman, N., Deng, X. L., Liu, A., Cerda-Smith, C. G., et al. (2023). Proceedings of the National Academy of Sciences, 120(38), e2221448120. doi.org/10.1073/pnas.2221448120
  4. Validation and comparison of the PECARN rule, Step-by-Step approach and Lab-score for predicting serious and invasive bacterial infections in young febrile infants
    2022 · Annals of the Academy of Medicine, Singapore
    Sutiman, N., Khoo, Z. X., Ong, G. Y.-K., Piragasam, R., & Chong, S.-L. (2022). Annals of the Academy of Medicine, Singapore, 51(10), 595–604. doi.org/10.47102/annals-acadmedsg.2022193
  5. A phase 1b study of OXIRI in pancreatic adenocarcinoma patients and its immunomodulatory effects
    2022 · International Journal of Cancer
    Ng, M., Chen, S., Ong, W. S., Balachander, A., Seet, A., Yeong, J., Sutiman, N., et al. (2022). International Journal of Cancer, 151(3), 435–449. doi.org/10.1002/ijc.34021
  6. Excellent survival outcomes of pediatric patients with acute myeloid leukemia treated with the MASPORE 2006 protocol
    2021 · Clinical Lymphoma Myeloma and Leukemia
    Sutiman, N., Nwe, M. S., Lai, E. E. N., Lee, D. K., Chan, M. Y., Yeoh, A. E.-J., Soh, S. Y., Leung, W., & Tan, A. M. (2021). Clinical Lymphoma Myeloma and Leukemia, 21(3), e290–e300. doi.org/10.1016/j.clml.2020.11.016
  7. Cooperative regulation of coupled oncoprotein translation and stability in triple-negative breast cancer by EGFR and CDK12
    2021 · BioRxiv
    Ang, H. X., Sutiman, N., Deng, X. L., Bartelt, L. C., Chen, Q., et al. (2021). BioRxiv, 2021.03.03.433762. doi.org/10.1101/2021.03.03.433762
  8. Protocol for the diagnostic performance of C-reactive protein, procalcitonin and interleukin-6 for serious bacterial infections among children ≤ 36 months old presenting with fever without source
    2021 · Health
    Sutiman, N., Yao, S. H. W., Goh, S. S. M., Sultana, R., & Chong, S. L. (2021). Health, 8.
  9. Alterations in drug pharmacokinetics in critically ill children supported on extracorporeal membrane oxygenation: A systematic review
    2020 · Australian Critical Care
    Sutiman, N., Watt, K., Hornik, C., Koh, J. C., Murphy, B., Chan, Y. H., & Lee, J. H. (2020). Australian Critical Care, 33, S2–S3. doi.org/10.1016/j.aucc.2020.04.006
  10. An intronic FTO variant rs16952570 confers protection against thiopurine-induced myelotoxicities in multiethnic Asian IBD patients
    2020 · The Pharmacogenomics Journal
    Chen, S., Tan, W. Z., Sutiman, N., Lim, C., Lee, S. S., Leong, W. F., et al. (2020). The Pharmacogenomics Journal, 20(3), 505–515. doi.org/10.1038/s41397-019-0126-9
  11. Pharmacokinetics alterations in critically ill pediatric patients on extracorporeal membrane oxygenation: A systematic review
    2020 · Frontiers in Pediatrics
    Sutiman, N., Koh, J. C., Watt, K., Hornik, C., Murphy, B., Chan, Y. H., & Lee, J. H. (2020). Frontiers in Pediatrics, 8, 260. doi.org/10.3389/fped.2020.00260
  12. Predictive role of NUDT15 variants on thiopurine-induced myelotoxicity in Asian inflammatory bowel disease patients
    2018 · Pharmacogenomics
    Sutiman, N., Chen, S., Ling, K. L., Chuah, S. W., Leong, W. F., et al. (2018). Pharmacogenomics, 19(1), 31–43. doi.org/10.2217/pgs-2017-0147
  13. EGFR mutation subtypes influence survival outcomes following first-line gefitinib therapy in advanced Asian NSCLC patients
    2017 · Journal of Thoracic Oncology
    Sutiman, N., Tan, S. W., Tan, E. H., Lim, W. T., Kanesvaran, R., et al. (2017). Journal of Thoracic Oncology, 12(3), 529–538. doi.org/10.1016/j.jtho.2016.11.2225
  14. Influence of the KDM4A rs586339 polymorphism on overall survival in Asian non-small-cell lung cancer patients
    2017 · Pharmacogenetics and Genomics
    Marvalim, C., Wong, J. X. G., Sutiman, N., Lim, W. T., Kanesvaran, R., et al. (2017). Pharmacogenetics and Genomics, 27(3), 120–123. doi.org/10.1097/fpc.0000000000000266
  15. Pharmacogenetics of ABCB5, ABCC5 and RLIP76 and doxorubicin pharmacokinetics in Asian breast cancer patients
    2017 · The Pharmacogenomics Journal
    Lal, S., Sutiman, N., Ooi, L. L., Wong, Z. W., Wong, N. S., Ang, P. C. S., & Chowbay, B. (2017). The Pharmacogenomics Journal, 17(4), 337–343. doi.org/10.1038/tpj.2016.17
  16. A phase I pharmacokinetic study of metronomic vinorelbine and sorafenib using two schedules in Asian non-small cell lung cancer (NSCLC) patients
    2017 · Annals of Oncology
    Chen, S., Sutiman, N., Shih, V., Tan, D., Ang, M. K., et al. (2017). Annals of Oncology, 28, x39–x40. doi.org/10.1093/annonc/mdx658.003
  17. Therapeutic drug monitoring of thiopurines in the management of Asian patients with inflammatory bowel disease
    2016 · Journal of Crohn's & Colitis
    Chuah, S. N. W., Delord, P., Sutiman, N., Leong, W. F., Kong, S. C., et al. (2016). Journal of Crohn's & Colitis, 10, S307–S308. doi.org/10.1093/ecco-jcc/jjw019.534
  18. Phase I study of oral vinorelbine in combination with erlotinib in advanced non-small cell lung cancer (NSCLC) using two different schedules
    2016 · PLoS One
    Sutiman, N., Zhang, Z., Tan, E. H., Ang, M. K., Tan, S.-W. D., et al. (2016). PLoS One, 11(5), e0154316. doi.org/10.1371/journal.pone.0154316
  19. Effects of oxaliplatin, capecitabine and irinotecan (OXIRI) on pancreatic ductal adenocarcinoma cell lines carrying different Kras mutational status
    2016 · Journal of Clinical Oncology
    Chowbay, B., Wong, J. X. G., Marvalim, C., Ng, S. L., Sutiman, N., & Leong, W. F. (2016). Journal of Clinical Oncology, 34(15_suppl), e15722–e15722. doi.org/10.1200/jco.2016.34.15_suppl.e15722
  20. Association of CYP2C19*2 and associated haplotypes with lower norendoxifen concentrations in tamoxifen-treated Asian breast cancer patients
    2016 · British Journal of Clinical Pharmacology
    Lim, J. S. L., Sutiman, N., Muerdter, T. E., Singh, O., Cheung, Y. B., et al. (2016). British Journal of Clinical Pharmacology, 81(6), 1142–1152. doi.org/10.1111/bcp.12886
  21. Pharmacogenetics of drug transporters in modulating imatinib disposition and treatment outcomes in chronic myeloid leukemia & gastrointestinal stromal tumor patients
    2016 · Pharmacogenomics
    Chen, S., Sutiman, N., & Chowbay, B. (2016). Pharmacogenomics, 17(17), 1941–1955. doi.org/10.2217/pgs-2016-0124
  22. Pharmacogenetics of UGT1A4, UGT2B7 and UGT2B15 and their influence on tamoxifen disposition in Asian breast cancer patients
    2016 · Clinical Pharmacokinetics
    Sutiman, N., Lim, J. S. L., Muerdter, T. E., Singh, O., Cheung, Y. B., et al. (2016). Clinical Pharmacokinetics, 55(10), 1239–1250. doi.org/10.1007/s40262-016-0402-7
  23. Pharmacogenetics of irinotecan, doxorubicin and docetaxel transporters in Asian and Caucasian cancer patients: A comparative review
    2016 · Drug Metabolism Reviews
    Chen, S., Sutiman, N., Zhang, C. Z., Yu, Y., Lam, S., Khor, C. C., & Chowbay, B. (2016). Drug Metabolism Reviews, 48(4), 502–540. doi.org/10.1080/03602532.2016.1226896
  24. Evaluation of severe neutropenia and diarrhea in Asian cancer patients receiving UGT1A1 genotype-guided irinotecan dosing
    2015 · Journal of Clinical Oncology
    Sutiman, N., Ramasamy, S., Ng, C. H. M., Choo, S. P., Lim, R. W., et al. (2015). Journal of Clinical Oncology, 33(15_suppl), e13572–e13572. doi.org/10.1200/jco.2015.33.15_suppl.e13572
  25. Influence of EGFR exon 19 mutation subtypes on survival outcomes in advanced stage Asian non-small cell lung cancer patients receiving TKI therapy
    2014 · European Journal of Cancer
    Chowbay, B., Singh, O., Sutiman, N., Tan, D. S. W., Lim, W. T., & Tan, E. H. (2014). European Journal of Cancer, 50, 32. doi.org/10.1016/s0959-8049(14)70212-6
  26. Pharmacogenetics and its relevance to clinical practice
    2013 · Annals of the Academy of Medicine, Singapore
    Sutiman, N., & Chowbay, B. (2013). Annals of the Academy of Medicine, Singapore, 42(9), 429–431. doi.org/10.47102/annals-acadmedsg.v42n9p429
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